English
norskBlar i forfatter "Naseer, Mohammed Umaer"
Viser treff 1-7 av 7
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AMR-Diag: Neural network based genotype-to-phenotype prediction of resistance towards β-lactams in Escherichia coli and Klebsiella pneumoniae
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-29)Antibiotic resistance poses a major threat to public health. More effective ways of the antibiotic prescription are needed to delay the spread of antibiotic resistance. Employment of sequencing technologies coupled with the use of trained neural network algorithms for genotype-to-phenotype prediction will reduce the time needed for antibiotic susceptibility profile identification from days to ... -
Erfaringsgjennomgang etter utvalgte utbrudd av covid-19 i Norge, desember 2020 – mars 2021
(Research report; Forskningsrapport, 2021-06)Denne rapporten beskriver en erfaringsgjennomgang av utvalgte covid-19 utbrudd i Norge, desember 2020 – mars 2021. Rapporten har blitt ledet av en intern arbeidsgruppe ved Folkehelseinstituttet (FHI) og er gjennomført i samarbeid med Helsedirektoratet, utvalgte kommuner og tilhørende statsforvaltere våren 2021. Hensikten har vært å oppsummere erfaringer og lære underveis, særlig knyttet til ... -
A Long-Term Low-Frequency Hospital Outbreak of KPC-Producing Klebsiella pneumoniae Involving Intergenus Plasmid Diffusion and a Persisting Environmental Reservoir
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Background: To study the molecular characteristics of a long-term, low frequency outbreak of blaKPC-2 in a low prevalence setting involving the hospital environment. Methodology/Principal Findings: KPC-producing bacteria were screened by selective chromogenic agar and Real-Time PCR. The presence of antibiotic resistance genes was ascribed by PCRs and subsequent sequencing, and the KPC-producing isolates ... -
Multi-Locus variable number of tandem repeat analysis for rapid and accurate typing of virulent multidrug resistant escherichia coli clones
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)One hundred E. coli isolates from Norway (n = 37), Sweden (n = 24), UK (n = 20) and Spain (n = 19), producing CTX-M-type - (n = 84), or SHV-12 (n = 4) extended spectrum β-lactamases, or the plasmid mediated AmpC, CMY-2 (n = 12), were typed using multi-locus sequence typing (MLST) and multi-locus variable number of tandem repeat analysis (MLVA). Isolates clustered into 33 Sequence Types (STs) and 14 ... -
Persistence of a pKPN3-like CTX-M-15-encoding IncFIIK plasmid in a Klebsiella pneumonia ST17 host during two years of intestinal colonization
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-04)Objectives To characterize the CTX-M-15-encoding plasmid in a Klebsiella pneumoniae ST17 strain, responsible for an outbreak at a Norwegian neonatal intensive care unit and subsequent colonization of affected children for up to two years. To identify plasmid-mediated features relevant for the outbreak dynamics, and to investigate the plasmids capability of horizontal transfer, its segregational ... -
Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencing
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-06)Bloodstream infections (BSI) and sepsis are major causes of morbidity and mortality worldwide. Blood culture-based diagnostics usually requires 1–2 days for identification of bacterial agent and an additional 2–3 days for phenotypic determination of antibiotic susceptibility pattern. With the escalating burden of antimicrobial resistance (AMR) rapid diagnostics becomes increasingly important to ... -
Within-population distribution of trimethoprim resistance in Escherichia coli before and after a community-wide intervention on trimethoprim use
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
